David Moyes has made seven changes for today’s game with Łukasz Fabiański included for the first time since surgery on his eye socket injury.
Kurt Zouma, Tomáš Souček, Jarrod Bowen and Lucas Paquetá are the tour who retain their spots from the team which beat AEK Larnaca 4-0 to reach the UEFA Europa Conference League last eight.
Danny Ings has been included as central striker and will be seeking his ninth Premier League goal of the season today, and third for the Irons.
Thilo Kehrer, Nayef Aguerd, Emerson, Declan Rice and Saïd Benrahma complete the list of recalled players by the manager.
An unchanged defence from the Irons’ last league fixture – a 1-1 draw with Aston Villa – sees Kehrer, Zouma, Aguerd and Emerson across the back four with Vladi Coufal, whio started two games for the Czech Republic relegated to the bench.
Joing him are Areola, Michail Antonio, Pablo Fornals, Manuel Lanzini, Angelo Ogbonna, Maxwel Cornet and Aaron Cresswell all available.
Gianluca Scamacca is not available for selection, with Moyes citing a knee issue in his pre-match press conference on Friday, with Flynn Downes completing the matchday squad.
West Ham United: Fabiański, Kehrer, Zouma, Aguerd, Emerson, Rice ©, Souček, Paquetá, Bowen, Benrahma, Ings
Subs: Areola (GK), Cresswell, Coufal, Fornals, Antonio, Lanzini, Downes, Cornet, Ogbonna
Southampton: Bazunu, Walker-Peters, Bednarek, Caleta-Car, Perraud, S.Armstrong, Ward-Prowse ©, Lavia, Elyounoussi, Walcott, Mara
Subs: McCarthy (GK), Lyanco, Aribo, Maitland-Niles, Diallo, Sulemana, Alcaraz, Oršić, Onuachu
Very disappointing team selection, mis use of players like Areola, Fornals and Lanzini, selecting Kehrer and Soucek playing ings up top on his own.
The guy has no clue. We can no longer accept this as fans we need to make our feelings clear to the owners – Moyes is single handedly leading us to relegation. Even if we win today this team selection is not acceptable.