The Irons will take part in the four-team Schalke 04 Cup in Germany in August.
The Hammers will join host club Schalke 04, Spanish Primera Division side Malaga CF and fellow Barclays Premier League outfit Newcastle United in the tournament, which will be held at the VELTINS-Arena over the weekend of Saturday 2/Sunday 3 August.
Rge stadium hosted the 2004 UEFA Champions League final, five matches at the 2006 FIFA World Cup and has a capacity of 61,482.
Two matches will be held on each day of the tournament, with a special points system in place and a special points system will be used.
Three points will be awarded to the winner of a match, and should a game end in a draw, it will go straight to a penalty shoot-out, with the winner receiving two points.
While West Ham have met Newcastle 125 times in their history, the competition will potentially see the Club meet both Schalke 04 and Malaga CF for the first time.
Ticket details for West Ham fans are yet to be confirmed and will follow on www. whufc.com in due course.