David Moyes has selected the same starting XI fopr the match against Sheffield United as was beaten at Liverpool last weekend.
A win would see him make his record against the Blades eight from eight with the Hammers looking for their tenth consecutive win against the bottom of the Premier League table.
Tomáš Souček is the one player to retain his place from the Carabao Cup outing against Lincoln City.
Jarrod Bowen will be seeking his fifth Premier League goal of the season and first on home soil.
Alphonse Areola continues in goal in the Premier League and is seeking his first clean sheet of the season.
Vladimír Coufal is at right-back, with Kurt Zouma skippering the side at centre-back alongside Nayef Aguerd, with Emerson at left-back.
Czech Souček starts in a midfield alongside Edson Álvarez and Brazil star Lucas Paquetá with James Ward-Prowse also in the middle of the park having scored score twice and assisted five goals in his first six games.
Bowen will support Michail Antonio in attack, with the Jamaica international targeting a sixth career goal against the Reds.
Mohammed Kudus, Pablo Fornals, Maxwel Cornet, Danny Ings and Saïd Benrahma are among those on the bench.
West Ham United: Areola, Coufal, Zouma ©, Aguerd, Emerson, Álvarez, Souček, Ward-Prowse, Paquetá, Bowen, Antonio
Subs: Fabiański (GK), Kehrer, Mavropanos, Ogbonna, Fornals, Kudus, Cornet, Benrahma, Ings
Sheffield United: Foderingham, Bogle, Egan ©, Ahmedhodžić, Robinson, Thomas, Souza, McAtee, Hamer, Archer, McBurnie
Subs: A.Davies (GK), Larouci, Trusty, Basham, Norwood, T.Davies, Ben Slimane, Traoré, Brewster
Referee: Graham Scott