The Gunners are also looking to win three consecutive league matches in the same season for the first time since February.
They have won three of their last four home league fixtures, drawing the other.
West Ham have lost four of their past six Premier League games but did win against Southampton last time out.
They have the worst form in the Premier League over the past eight matches.
West Ham have lost 22 points from a winning position this campaign, five more than any other club.
The Hammers have a point fewer than they did at this stage in 2010-11, the most recent season in which they were relegated.
Each of Sebastien Haller’s 31 goals in the major European leagues has been scored inside the penalty area (seven for West Ham and 24 for Eintracht Frankfurt).
David Moyes hasn’t won any of his 15 Premier League away games against Arsenal (D4, L11). No manager in Premier League history has ever gone more away fixtures against one team without winning.