With Andy Carroll employed through the middle, any aerial service looks set to come from Pablo Zabaleta and Aaron Creswell with Ayew and Lanzini on the flanks but with licence to cut inside of course.
The absence of Michail Antonio is making team selection difficult and young Nathan Holland’s ruptured hamstring injury means that manager David Moyes has had to look at a different system to used previously this season.
There was a genuine feeling inside the camp that Holland’s time had come and the injury is a massive disappointment.
Winston Reid remains a doubt with much depending on whether he is considered fit and injury free after racing back from New Zealand’s World Cup play off match.
Possible line-up: Hart, Zaba, Reid, Rice, Cresswell; Noble, Kouyate, Obiang, Lanzini, Ayew, Carroll.