Manuel Lanzini, Sofiane Feghouli and Havard Nordtveit are also back from injuries but Michail Antonio looks certain to get the shout on the right wing berth.
Watford have worries with defender Brice Dje Djedje doubtful with a foot problem and Craig Cathcart, troubled by a groin strain.
Argentina midfielder Roberto Pereyra could make his first start, having scored when coming off the bench in the home defeat by Arsenal before the international break. but Watford will check on defender
Adrian Mariappa has rejoined the Hornets after being released by Crystal Palace earlier this summer, and 20-year-old Brazilian midfielder Kenedy could be included after signing on a season loan from Chelsea.
Hammers likely line up: Adrian; Byram, Reid, Ogbonna Masuaku; Antonio, Noble, Kouyate, Lanzini, Payet, Zaza