Nearly 63% predict another West Ham defeat, 21% for the draw and 16% for the West Home win.
West Ham is vying to complete their first league double over Chelsea since the 2002-03 season.
The Hammers have only lost one of the past five meetings against Chelsea, winning two and drawing two.
The Hammers could suffer four consecutive Premier League defeats without scoring for the first time since October 2006.
They could also lose four home Premier League London derbies in a row for the first time.
David Moyes’ side have dropped a league-high 22 points from winning positions this season.
Defeat would ensure the Hammers equal their Premier League club record of nine home defeats in a season.
Moyes’ first win as West Ham manager was 1-0 against Chelsea in December 2017.
Chelsea have only kept one clean sheet in their 15 Premier League away matches this season.