Crystal Palace striker Fraizer Campbell has suffered a hamstring injury and is set to miss the trip to Upton park this weekend.
The front man has seen much action under Alan Pardew but came off against Arsenal last week and could be out for around a month.
Palace are also without Marouane Chamakh leaving a choice of Glenn Murray or Dwight Gayle to lead the line although Shola Ameobi may enter the reckong.
West Ham are without Carlton Cole and Andy Carroll so new-boy Nene (pictured above) is set to be in the squad for the first time.